410 research outputs found

    Cultural Perspective on Mental Health and Disaster of Women Affected by the 2010 Mt. Merapi Eruption

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    Third Student Poster Presentation. Presenter: Lori Murphy - "Cultural Perspective on Mental Health and Disaster of Women Affected by the 2010 Mt. Merapi Eruption"The Ohio State University College of Social Wor

    Cultural Perspective on Mental Health and Disaster of Women Affected by the 2010 Mt. Merapi Eruption

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    Third Student Poster Presentation. Presenter: Lori Murphy - "Cultural Perspective on Mental Health and Disaster of Women Affected by the 2010 Mt. Merapi Eruption"The Ohio State University College of Social Wor

    They Changed the Rules Again?

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    IACRL program presented on the mechanics of cataloging electronic resources at the ILA Annual Conference

    Effect of cultivar and soil characteristics on nutritional value in organic and conventional wheat

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    Evidence of greater nutritional value in organic crops is currently a subject of intense debate. Our objectives in this study were to test for grain mineral concentration in 35 winter wheat cultivars in paired organic and conventional systems, and to determine the influence of cultivar, soil characteristics and farming system on mineral concentration. Here we report preliminary results that show that the grain mineral concentration in organic wheat was higher for copper (Cu), magnesium (Mg), manganese (Mn), phosphorus (P) and zinc (Zn) and lower in calcium (Ca), than the grain mineral concentration in conventional wheat. No difference was found between systems for iron (Fe) concentration. Cultivar was significant in determining mineral concentration for Ca, Cu, Mg, Mn and P. Soil mineral concentration was not responsible for grain mineral concentration, with the exception of P. The organic wheat farming systems had higher grain mineral concentrations of Cu, Mg, Mn, P and Zn than the conventional systems, possibly due in part to increased soil organic matter and pH in the organic systems. Growing specific cultivars capable of exploiting particular soil conditions may be necessary in order to optimize the nutritional value in organic farming systems

    Can The Insertion Of An E. coli Shine-Dalgarno Sequence Upstream Of M. ruber proA Of The proBA Operon Enhance Its Expression, As Measured By A Complementation Assay Using E. coli Null Strains?

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    The process by which the thermophilic bacteria Meiothermus ruber (M. ruber) synthesizes the amino acid proline is examined in this paper. In the well-studied E. coli system, proline biosynthesis involves three enzymes ProA, ProB and ProC; proA and proB form the proBA operon and both proA and proB possess an upstream Shine-Delgarno sequence; and ProB is functionally dependent on ProA as components of a ProBA complex. In previous studies in Dr. Scott’s lab, the putative M. ruber proA (locus tag Mrub1079), proB (Mrub1080) and proC (Mrub1345) genes were cloned into the pKt1 expression vector, transformed into the corresponding E. coli null strains, and tested for complementation. In addition, an Mrub1080-1079 clone was tested for complementation against E. coli proA - and proB - null strains. The M. ruber gene Mrub1345 successfully complemented E. coli proC - null strain but complementation of Mrub1079, Mrub1080 and Mrub1080-1079 clones produced inconclusive results. In this paper, we demonstrate conclusively that Mrub1079 and Mrub1080 complement their respective E. coli null strains, thereby confirming the function of the M. ruber genes in proline biosynthesis. The outcome of the complementation test was not enhanced by testing an intact proBA operon, or by adding an E. coli version of a Shine-Delgarno sequence upstream of the Mrub1079 in the Mrub1080-1079 clone

    Persistent Peripheral Inflammation Attenuates Morphine-induced Periaqueductal Gray Glial Cell Activation and Analgesic Tolerance in the Male Rat

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    Morphine is among the most prevalent analgesics prescribed for chronic pain. However, prolonged morphine treatment results in the development of analgesic tolerance. An abundance of evidence has accumulated indicating that CNS glial cell activity facilitates pain transmission and opposes morphine analgesia. While the midbrain ventrolateral periaqueductal gray (vlPAG) is an important neural substrate mediating pain modulation and the development of morphine tolerance, no studies have directly assessed the role of PAG‐glia. Here we test the hypothesis that morphine‐induced increases in vlPAG glial cell activity contribute to the development of morphine tolerance. As morphine is primarily consumed for the alleviation of severe pain, the influence of persistent inflammatory pain was also assessed. Administration of morphine, in the absence of persistent inflammatory pain, resulted in the rapid development of morphine tolerance and was accompanied by a significant increase in vlPAG glial activation. In contrast, persistent inflammatory hyperalgesia, induced by intraplantar administration of Complete Freund’s Adjuvant (CFA), significantly attenuated the development of morphine tolerance. No significant differences were noted in vlPAG glial cell activation for CFA‐treated animals versus controls. These results indicate that vlPAG glia are modulated by a persistent pain state, and implicate vlPAG glial cells as possible regulators of morphine tolerance. The development of morphine tolerance represents a significant impediment to its use in the management of chronic pain. We report that morphine tolerance is accompanied by increased glial cell activation within the vlPAG, and that the presence of a persistent pain state prevented vlPAG glial activation and attenuated morphine tolerance

    Magnetic Resonance Imaging and Three-Dimensional Reconstructions of the Brain of a Fetal Common Dolphin, Delphinus delphis

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    To demonstrate the kinds of data that can be obtained non-destructively and non-invasively from preserved museum specimens using modern imaging technology the head region of a whole body fetal specimen of the common dolphin, Delphinus delphis, aged 8–9 months post-conception, was scanned using Magnetic Resonance Imaging (MRI). Series of scans were obtained in coronal, sagittal and horizontal planes. A digital three-dimensional reconstruction of the whole brain was prepared from the coronal series of scans. Sectional areas and three-dimensional volumes were obtained of the cerebral hemispheres and of the brainstemplus-cerebellum. Neuroanatomical features identified in the scans include the major sulci of the cerebral hemispheres, well-differentiated regions of gray and white matter, the mesencephalic, pontine, and cervical flexures, the “foreshortened’’ appearance of the forebrain, and the large auditory inferior colliculi. These findings show that numerous features of the fetal common dolphin brain can be visualized and analyzed from MRI scans

    Optimizing Digital Integrated Care via MicroĂą Randomized Trials

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/144704/1/cpt1079.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/144704/2/cpt1079_am.pd

    Policing Political Ads: An Analysis of Five Leading Newspapers' Responses to 1992 Political Advertisements

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    Lori Melton McKinnon is an assistant professor of advertising and public relations in the College of Communication at the University of Alabama. Lynda Lee Kaid is a professor in the Department of Communication and the director of the Political Communication Center at the University of Oklahoma; Cynthia K. Acree is an account executive for the integrated marketing communications firm The Evans Group in Dallas, Texas; and Janet Murphy is an assistant professor in the Department of Communication at Oklahoma Christian University.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline
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